Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
| Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
| Upregulated in class | wtNotch |
| GeneSet | BIOCARTA_INACTIVATION OF GSK3 BY AKT CAUSES ACCUMULATION OF B-CATENIN IN ALVEOLAR MACROPHAGES |
| Enrichment Score (ES) | -0.6614983 |
| Normalized Enrichment Score (NES) | -1.4604435 |
| Nominal p-value | 0.028436018 |
| FDR q-value | 0.6807923 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | FRAT1 | 780520 2120731 | 607 | 0.556 | 0.0385 | No | ||
| 2 | CD14 | 5570600 | 1422 | 0.309 | 0.0342 | No | ||
| 3 | NFKBIA | 1570152 | 2224 | 0.187 | 0.0150 | No | ||
| 4 | BTRC | 3170131 | 2963 | 0.109 | -0.0108 | No | ||
| 5 | IRAK1 | 4120593 | 3363 | 0.084 | -0.0215 | No | ||
| 6 | TLR4 | 1690167 2650369 3850333 | 3585 | 0.073 | -0.0240 | No | ||
| 7 | NKD2 | 1170731 | 3627 | 0.071 | -0.0172 | No | ||
| 8 | GJA1 | 5220731 | 4258 | 0.049 | -0.0448 | No | ||
| 9 | KREMEN2 | 110025 | 4284 | 0.049 | -0.0399 | No | ||
| 10 | WIF1 | 7100184 | 5667 | 0.024 | -0.1112 | No | ||
| 11 | DKK2 | 3610433 | 9026 | 0.005 | -0.2913 | No | ||
| 12 | PIK3R1 | 4730671 | 9416 | 0.004 | -0.3118 | No | ||
| 13 | FZD1 | 3140215 | 9544 | 0.003 | -0.3182 | No | ||
| 14 | MYD88 | 2100717 | 9943 | 0.002 | -0.3393 | No | ||
| 15 | DKK1 | 1940215 | 11115 | -0.001 | -0.4022 | No | ||
| 16 | AKT1 | 5290746 | 11364 | -0.002 | -0.4153 | No | ||
| 17 | PROC | 6520270 | 12691 | -0.007 | -0.4858 | No | ||
| 18 | IKBKG | 3450092 3840377 6590592 | 13769 | -0.014 | -0.5420 | No | ||
| 19 | PIK3CA | 6220129 | 13948 | -0.016 | -0.5496 | No | ||
| 20 | CSNK2A1 | 1580577 | 14243 | -0.020 | -0.5628 | No | ||
| 21 | RELA | 3830075 | 14477 | -0.024 | -0.5724 | No | ||
| 22 | WNT1 | 4780148 | 14605 | -0.026 | -0.5759 | No | ||
| 23 | EHHADH | 6200315 | 15139 | -0.043 | -0.5990 | No | ||
| 24 | TIRAP | 60129 6400097 | 15259 | -0.048 | -0.5993 | No | ||
| 25 | AXIN1 | 3360358 6940451 | 15348 | -0.051 | -0.5975 | No | ||
| 26 | LRP6 | 5130064 | 15662 | -0.071 | -0.6053 | No | ||
| 27 | LY96 | 630519 | 16707 | -0.181 | -0.6383 | Yes | ||
| 28 | PDPK1 | 6650168 | 16837 | -0.204 | -0.6191 | Yes | ||
| 29 | NKD1 | 1340286 | 16864 | -0.209 | -0.5937 | Yes | ||
| 30 | IKBKB | 6840072 | 16922 | -0.218 | -0.5689 | Yes | ||
| 31 | TOLLIP | 5340601 6200465 | 16937 | -0.221 | -0.5413 | Yes | ||
| 32 | GSK3B | 5360348 | 17003 | -0.232 | -0.5152 | Yes | ||
| 33 | LEF1 | 2470082 7100288 | 17114 | -0.255 | -0.4884 | Yes | ||
| 34 | DVL1 | 5900450 6510162 | 17943 | -0.530 | -0.4651 | Yes | ||
| 35 | CHUK | 7050736 | 17998 | -0.557 | -0.3967 | Yes | ||
| 36 | EIF2AK2 | 870239 | 18055 | -0.588 | -0.3244 | Yes | ||
| 37 | PPP2R5D | 4010156 380408 5550112 5670162 | 18449 | -0.968 | -0.2216 | Yes | ||
| 38 | CCND1 | 460524 770309 3120576 6980398 | 18589 | -1.801 | 0.0015 | Yes |
